Article
No increase in prevalence of hepatitis B surface antigen mutant in a population of children and adolescents who were fully covered by universal infant immunization.
The Journal of infectious diseases - 15 Apr 2010
Hsu Hong-Yuan, Chang Mei-Hwei, Ni Yen-Hsuan, Chiang Cheng-Lun, Chen Huey-Ling, Wu Jia-Feng, Chen Pei-Jer
Abstract excerpt
BACKGROUND: Mutants of the a determinant of hepatitis B surface antigen (HBsAg) can escape neutralization by vaccine-induced antibodies and prevail in an immunized population. METHODS: We evaluated the a mutants in a pediatric population surveyed in 2004 and compared these findings with the data of previous surveys. RESULTS: There were 38 children and 74 adolescents who were HBsAg positive, and serum hepatitis B...
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