Article
Changes of hepatitis B surface antigen variants in carrier children before and after universal vaccination in Taiwan.
Hepatology (Baltimore, Md.) - 1 Nov 1999
Hsu H Y, Chang M H, Liaw S H, Ni Y H, Chen H L
Abstract excerpt
Mutants of a determinant of hepatitis B surface antigen (HBsAg) identified in vaccinated children pose a potential threat to long-term success of vaccination programs. We examined the mutants of a determinant (residues 110-160) of HBsAg in hepatitis B virus (HBV) DNA-positive children identified during previous serosurveys in Taipei undertaken just before (1984), 5 years after (1989), and 10 years after (1994)...
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