Article
A serological and molecular survey of hepatitis B in children 15 years after inception of the national hepatitis B vaccination program in eastern China.
Journal of medical virology - 1 Sept 2009
Dong Ying, Liu She-Lan, Zhai Xiang-Jun, Zhu Feng-Cai, Pan Hao, Yu Jia-Xi, Chen Yin-Zhong, Xie Yi-Rui, Zhang Xiao-Yu, Zhang Hong-Mei, Li Lan-Juan, Wang Hua, Ruan Bing
Abstract excerpt
The emergence of mutations in the hepatitis B virus (HBV) S gene has threatened the long-term success of vaccination programs since the worldwide introduction of effective vaccines against hepatitis B. This study was conducted on 5,407 children (0-8 years old) in eastern China in 2007. We analyzed the prevalence of HBsAg, anti-HBs, and "a"-determinant mutations in the HBV S gene by microparticle enzyme...
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