Article
Survey of hepatitis B surface variant infection in children 15 years after a nationwide vaccination programme in Taiwan.
Gut - 1 Oct 2004
Hsu H-Y, Chang M-H, Ni Y-H, Chen H-L
Abstract excerpt
BACKGROUND: It is not known whether hepatitis B virus (HBV) with mutations in the a determinant (amino acids (aa) 121-149) of the hepatitis B surface antigen (HBsAg) affect vaccination efficacy. AIM: To investigate the prevalence and clinical significance of these mutants in children, 15 years after universal vaccination in Taiwan. METHODS: Nucleotide sequences encoding the a determinant region (aa 110-160) of...
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