Mutations in the 'a' determinant of hepatitis B surface antigen among Chinese infants receiving active postexposure hepatitis B immunization.

doi:10.1016/s0264-410x(97)00182-5

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Article

Mutations in the 'a' determinant of hepatitis B surface antigen among Chinese infants receiving active postexposure hepatitis B immunization.

Vaccine - 1 Jan 2000

He J W, Lu Q, Zhu Q R, Duan S C, Wen Y M

Abstract excerpt

Twenty-four infants who became positive to the surface antigen of hepatitis B virus (HBsAg) despite a complete course of active postexposure immunization with plasma derived hepatitis B vaccine were studied. The polymerase chain reaction amplified products of the common neutralizing epitope 'a' d...

Topics

Amino Acid Sequence
China
Epitopes
Hepatitis B
Hepatitis B Surface Antigens
Hepatitis B Vaccines
Hepatitis B virus
Humans
Immunization
Infant
Infant, Newborn
Molecular Sequence Data
Mutation
Treatment Failure

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