Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Kinetic modeling reveals a common death niche for newly formed and mature B cells.

PloS one - 2 Mar 2010

Shahaf Gitit, Cancro Michael P, Mehr Ramit

Abstract excerpt

BACKGROUND: B lymphocytes are subject to elimination following strong BCR ligation in the absence of appropriate second signals, and this mechanism mediates substantial cell losses during late differentiation steps in the bone marrow and periphery. Mature B cells may also be eliminated through this mechanism as well as through normal turnover, but the population containing mature cells destined for elimination...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocytes
Share to Bone Marrow Cells
Share to Cell Death

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Movement

Share to Computer Simulation

Share to Models, Statistical

Share to Models, Theoretical

Share to Spleen

Source

Open in PubMed Open full text

Identifiers

PMID: 20209168
DOI: 10.1371/journal.pone.0009497
PMCID: PMC2830485

Genes

BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Kinetic modeling reveals a common death niche for newly formed and mature B cells.PMID 20209168Read ↗

Generation of peripheral B cells occurs via two spatially and temporally distinct pathways.Semantic proximity Read ↗

Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation.Semantic proximity Read ↗

Novel human transitional B cell populations revealed by B cell depletion therapy.Semantic proximity Read ↗

Transitional B cells: step by step towards immune competence.Semantic proximity Read ↗

Quantitative modeling of the terminal differentiation of B cells and mechanisms of lymphomagenesisSemantic proximity Read ↗

Quantification of T lymphocyte dynamics in vivoSemantic proximity Read ↗

Bcl-2 supports survival and metabolic fitness of quiescent tissue-resident ILC3.Semantic proximity Read ↗

Potentially autoreactive naturally occurring transitional T3 B lymphocytes exhibit a unique signaling profile.Semantic proximity Read ↗

Identification and Characterization of a Human CD5+ Pre-Naive B Cell PopulationSemantic proximity Read ↗

Transitional B cell fate is associated with developmental stage-specific regulation of diacylglycerol and calcium signaling upon B cell receptor engagement.Semantic proximity Read ↗

Characterization of a late transitional B cell population highly sensitive to BAFF-mediated homeostatic proliferation.Semantic proximity Read ↗

FOXO3 is differentially required for CD8+ T-cell death during tolerance versus immunity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.