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Article

HFE mutations in alpha-1-antitrypsin deficiency: an examination of cirrhotic explants.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 May 2010

Lam Maggie, Torbenson Michael, Yeh Matthew M, Vivekanandan Perumal, Ferrell Linda

Abstract excerpt

Increased iron deposition is often seen in liver explants with alpha-1-antitrypsin deficiency, but it remains unclear if this is a nonspecific effect of end-stage liver disease or if individuals with alpha-1-antitrypsin deficiency and excess iron are at increased risk for HFE mutations. To furthe...

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Source

Identifiers

PMID: 20208481
DOI: 10.1038/modpathol.2010.42

Genes

HFE

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20208481-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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