Article
Roles of iron and HFE mutations on severity and response to therapy during retreatment of advanced chronic hepatitis C.
Gastroenterology - 1 Nov 2006
Bonkovsky Herbert L, Naishadham Deepa, Lambrecht Richard W, Chung Raymond T, Hoefs John C, Nash S Russell, Rogers Thomas E, Banner Barbara F, Sterling Richard K, Donovan John A, Fontana Robert J, Di Bisceglie Adrian M, Ghany Marc G, Morishima Chihiro
Abstract excerpt
BACKGROUND & AIMS: Iron overload may cause or contribute to hepatic injury and fibrosis. Mutations in the HFE gene may influence development or progression of chronic liver disease by increasing iron stores or modulating immune responses. The aim of this work was to assess the influence of HFE mu...
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