Article
Hereditary hemochromatosis in liver transplantation.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society - 1 Jan 1999
Fiel M I, Schiano T D, Bodenheimer H C, Thung S N, King T W, Varma C R, Miller C M, Brunt E M, Starnes S, Prass C, Wolff R K, Bacon B R
Abstract excerpt
A candidate gene, HFE, was recently described in patients with hereditary hemochromatosis (HH) and found to contain a missense mutation leading to a cysteine to tyrosine substitution (C282Y). A second mutation, H63D, was also found in the gene. This study was undertaken to determine the HFE genot...
Topics
- Adult
- Aged
- Female
- Genotype
- HLA Antigens
- Hemochromatosis
- Histocompatibility Antigens Class I
- Homozygote
- Humans
- Iron
- Liver Cirrhosis
- Liver Diseases
- Liver Transplantation
- Male
- Middle Aged
- Mutation