Article
Histological evaluation of iron in liver biopsies: relationship to HFE mutations.
The American journal of gastroenterology - 1 Jul 2000
Brunt E M, Olynyk J K, Britton R S, Janney C G, Di Bisceglie A M, Bacon B R
Abstract excerpt
OBJECTIVE: Hepatic iron overload is observed in many forms of chronic liver disease. Hereditary hemochromatosis (HH) results in hepatic iron overload and is associated with 2 missense mutations in the HFE gene. The aim of this study was to define the usefulness of the histological pattern of iron deposition in determining the probability of an iron-loaded patient having HFE-related iron overload. METHODS: This...
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