Article
Polymorphisms in the human apolipoprotein E receptor 2 gene in Japanese sporadic Alzheimer's disease patients.
Bioscience, biotechnology, and biochemistry - 1 Jan 2010
Hosoda Akemi, Inoue Takashi, Mao Chang C, Jeong Young-Hee, Yamagishi Azumi, Ye Mingjuan, Yamamoto Tokuo, Kim Dong-Ho, Saeki Shigeru
Abstract excerpt
Apolipoprotein E (apoE) polymorphism is associated with onset of Alzheimer's disease (AD). We found seven polymorphisms in apoE receptor 2 (ApoER2), an apoE-binding receptor, in Japanese sporadic AD patients, but no association of ApoER2 polymorphisms with AD. We consider that the functions of ApoER2 in the brain may be compensated for by those of other apoE-binding receptors such as VLDL receptor.
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.