Apolipoprotein E polymorphism in Japanese patients with Alzheimer's disease or vascular dementia.

doi:10.1136/jnnp.57.11.1414

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Article

Apolipoprotein E polymorphism in Japanese patients with Alzheimer's disease or vascular dementia.

Journal of neurology, neurosurgery, and psychiatry - 1 Nov 1994

Kawamata J, Tanaka S, Shimohama S, Ueda K, Kimura J

Abstract excerpt

Apolipoprotein E (ApoE) plays a key part in lipid metabolism both in the liver, and in the CNS. To clarify the association of ApoE polymorphism with Alzheimer's disease and vascular dementia in Japan, 13 patients with early onset (age > or = 65) sporadic Alzheimer's disease, 40 patients with late...

Topics

Adult
Age of Onset
Aged
Alleles
Alzheimer Disease
Apolipoproteins E
Brain
DNA
Dementia, Vascular
Genome
Genotype
Humans
Japan
Middle Aged
Polymerase Chain Reaction
Polymorphism, Genetic

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