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Article

Quantifying EGFR alterations in the lung cancer genome with nanofluidic digital PCR arrays.

Clinical chemistry - 1 Apr 2010

Wang Jun, Ramakrishnan Ramesh, Tang Zhe, Fan Weiwen, Kluge Amy, Dowlati Afshin, Jones Robert C, Ma Patrick C

Abstract excerpt

BACKGROUND: The EGFR [epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)] gene is known to harbor genomic alterations in advanced lung cancer involving gene amplification and kinase mutations that predict the clinical response to EGFR-targeted inhib...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20207772
DOI: 10.1373/clinchem.2009.134973

Genes

EGFR
RPP30

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20207772-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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