Article
Quantification of plasma EGFR mutations in patients with lung cancers: Comparison of the performance of ARMS-Plus and droplet digital PCR.
Lung cancer (Amsterdam, Netherlands) - 1 Dec 2017
Wang Lin, Guo Qiaomei, Yu Wenjun, Qiao Lihua, Zhao Mingna, Zhang Chenzi, Hu Xiaomeng, Yang Guohua, Xiong Liwen, Lou Jiatao
Abstract excerpt
OBJECTIVES: EGFR mutation is a key factor to predict EGFR-TKI efficacy. However, a significant number of advanced patients do not have sufficient tumor specimens for molecular testing. Also, there is a lack of quantitative assay to analyze the mutant abundance. This study aims to evaluate the detection efficiency and clinical feasibility of a new platform, namely ARMS-Plus, for the detection and quantification of...
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