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Article

Usefulness of nanofluidic digital PCR arrays to quantify T790M mutation in EGFR-mutant lung adenocarcinoma.

Cancer genomics & proteomics - 1 Jan 2000

Isobe Kazutoshi, Hata Yoshinobu, Tochigi Naobumi, Kaburaki Kyohei, Kobayashi Hiroshi, Makino Takashi, Otsuka Hajime, Ishida Fumiaki, Hirota Nao, Sano Go, Sugino Keishi, Sakamoto Susumu, Takai Yujiro, Shibuya Kazutoshi, Iyoda Akira, Homma Sakae

Abstract excerpt

AIM: The present pilot study assessed the usefulness of nanofluidic digital polymerase chain reaction (PCR) arrays in epidermal growth factor receptor (EGFR)-mutant lung adenocarcinoma after tyrosine kinase inhibitor (TKI) resistance. PATIENTS AND METHODS: We enrolled 12 patients with primary lung adenocarcinoma with sensitive EGFR mutation-confirmed T790M status by re-biopsy after TKI resistance. Nanofluidic...

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PMID: 25560642

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EGFR

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