Interaction between radiation and drug damage in mammalian cells. V. DNA damage and repair induced in LZ cells by adriamycin and/or radiation.

Article

Interaction between radiation and drug damage in mammalian cells. V. DNA damage and repair induced in LZ cells by adriamycin and/or radiation.

Radiation research - 1 Apr 1991

Sognier M A, Eberle R L, Zhang Y, Belli J A

Abstract excerpt

A multi-drug-resistant cell line selected in increasing concentrations of Adriamycin and designated LZ (J. A. Belli, Radiat. Res. 119, 88-100, 1989) is shown to exhibit a survival response characterized by radiation sensitivity and Adriamycin resistance. To determine if this response is due to al...

Topics

Animals
Cell Line
Cell Survival
DNA
DNA Damage
Dose-Response Relationship, Drug
Dose-Response Relationship, Radiation
Doxorubicin
Drug Resistance, Microbial
Mutation

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