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Article

Comparison of radon-daughter-induced effects in repair-proficient and repair-deficient CHO cell lines.

Environmental and molecular mutagenesis - 1 Jan 1990

Schwartz J L, Shadley J D, Atcher R W, Tang J, Whitlock J L, Rotmensch J

Abstract excerpt

The radiobiological effects of the radon daughter 212Bi were investigated in the Chinese hamster ovary cell line AA8 and its radiosensitive derivative EM9. EM9 cells rejoin radiation-induced DNA strand breaks more slowly than do AA8 cells. Three endpoints were examined: cell killing, G2-induced chromosome aberration frequency, and mutation induction at the hypoxanthine (guanine) phosphoribosyltransferase (HGPRT)...

Topics

Animals
Bismuth
Cell Line
Chromosome Aberrations
Chromosomes
Cricetinae
Cricetulus
DNA Repair
Hypoxanthine Phosphoribosyltransferase
Mutagens
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Pentetic Acid

Radioisotopes

Radon

Thioguanine

X-Rays

Source

Identifiers

PMID: 2209573
DOI: 10.1002/em.2850160305

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2209573-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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