Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Modulation of radiation-induced strand break repair by cisplatin in mammalian cells

1 Jan 1998

Abstract excerpt

PURPOSE: To investigate the repair of ionizing radiation-induced DNA lesions in human skin fibroblasts in the presence of cisplatin-DNA adducts and to determine the persistence of DNA repair inhibition by cisplatin. MATERIALS AND METHODS: Normal human fibroblasts (AG 1522) treated with cisplatin were exposed to 4 Gy 60Co gamma-radiation and assayed for repair of radiation-induced damage under growth-permissive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogens and Genotoxicity Assessment
Share to DNA Repair Mechanisms
Share to Effects of Radiation Exposure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9687976
DOI: 10.1080/095530098141735

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Modulation of radiation-induced strand break repair by cisplatin in mammalian cellsPMID 9687976Read ↗

Examining the non-homologous repair process following cisplatin and radiation treatments.Semantic proximity Read ↗

Evidence for Complexity at the Nanometer Scale of Radiation-Induced DNA DSBs as a Determinant of Rejoining KineticsSemantic proximity Read ↗

Evaluation of adaptive responses to cisplatin in normal and mutant cell lines with mutations in recombination repair pathways.Semantic proximity Read ↗

Induction and Rejoining of DNA Double-Strand Breaks in Normal Human Skin Fibroblasts after Exposure to Radiation of Different Linear Energy Transfer: Possible Roles of Track Structure and Chromatin OrganizationSemantic proximity Read ↗

Dose- and time-response relationships for lethal mutations and chromosomal instability induced by ionizing radiation in an immortalized human keratinocyte cell line.Semantic proximity Read ↗

Radiation-induced DNA double-strand break rejoining in human tumour cellsSemantic proximity Read ↗

Alterations in the Progression of Cells through the Cell Cycle after Exposure to Alpha Particles or Gamma RaysSemantic proximity Read ↗

Relationship between cellular radiosensitivity and non-repaired double-strand breaks studied for different growth states, dose rates and plating conditions in a normal human fibroblast lineSemantic proximity Read ↗

Radiosensitivity of human tumour cells is correlated with the induction but not with the repair of DNA double-strand breaksSemantic proximity Read ↗

Rejoining of DNA fragments produced by radiations of different linear energy transferSemantic proximity Read ↗

Differential response of human fibroblasts to the cytotoxic and mutagenic effects of UV radiation in different phases of the cell cycle.Semantic proximity Read ↗

Correlation between cellular radiosensitivity and non-repaired double-strand breaks studied in nine mammalian cell linesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.