Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms of the DNA repair gene MGMT and risk and progression of head and neck cancer.

DNA repair - 4 May 2010

Zhang Zhengdong, Wang Luo, Wei Sheng, Liu Zhensheng, Wang Li-E, Sturgis Erich M, Wei Qingyi

Abstract excerpt

Methylating agents are involved in carcinogenesis, and the DNA repair protein O(6)-methylguanine-DNA methyltransferase (MGMT) removes methyl group from O(6)-methylguanine. Genetic variation in DNA repair genes has been shown to contribute to susceptibility to squamous cell carcinoma of the head a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Disease Progression
Share to DNA Modification Methylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair

Share to DNA Repair Enzymes

Share to Head and Neck Neoplasms

Share to Tumor Suppressor Proteins

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 20206583
DOI: 10.1016/j.dnarep.2010.02.006
PMCID: PMC2883263

Genes

MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20206583-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms of the DNA repair gene MGMT and risk and progression of head and neck cancer.PMID 20206583Read ↗

The role of MGMT polymorphisms rs12917 and rs11016879 in head and neck cancer risk and prognosis.Semantic proximity Read ↗

Polymorphisms of methionine synthase and methionine synthase reductase and risk of squamous cell carcinoma of the head and neck: a case-control analysis.Semantic proximity Read ↗

O6-methylguanine-DNA methyltransferase gene coding region polymorphisms and oral cancer risk.Semantic proximity Read ↗

Polymorphisms of the DNMT3B gene and risk of squamous cell carcinoma of the head and neck: a case-control study.Semantic proximity Read ↗

Associations among smoking, MGMT hypermethylation, TP53-mutations, and relapse in head and neck squamous cell carcinoma.Semantic proximity Read ↗

Association between genetic polymorphisms in DNA mismatch repair-related genes with risk and prognosis of head and neck squamous cell carcinoma.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase polymorphisms and risk of squamous cell carcinoma of the head and neck: a case-control analysis.Semantic proximity Read ↗

Molecular epidemiology of DNA repair gene polymorphisms and head and neck cancerSemantic proximity Read ↗

Analysis of Association Between MGMT and p53 Gene Single Nucleotide Polymorphisms and Laryngeal Cancer.Semantic proximity Read ↗

Association between 11 genetic polymorphisms in folate-metabolising genes and head and neck cancer risk.Semantic proximity Read ↗

GSTM1, GSTT1, and the risk of squamous cell carcinoma of the head and neck: a mini-HuGE review.Semantic proximity Read ↗

Polymorphisms and haplotypes in methylenetetrahydrofolate reductase gene and head and neck squamous cell carcinoma risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.