Article
Evidence that the C-terminus of OprM is involved in the assembly of the VceAB-OprM efflux pump.
FEBS letters - 16 Apr 2010
Bai Jiangping, Mosley Lakysha, Fralick Joe A
Abstract excerpt
Although the architecture of tripartite multiple drug resistance (MDR) efflux pumps of Gram-negative bacteria has been well characterized, the means by which the components recognize each other and assemble into a functional pump remains obscure. In this study we present evidence that the C-terminal domain of the Pseudomonas aeruginosa OprM and the alpha-helical hairpin domain of Vibrio cholerae VceA play an...
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