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Article

Dynamics of Intact MexAB-OprM Efflux Pump: Focusing on the MexA-OprM Interface.

Scientific reports - 28 Nov 2017

López Cesar A, Travers Timothy, Pos Klaas M, Zgurskaya Helen I, Gnanakaran S

Abstract excerpt

Antibiotic efflux is one of the most critical mechanisms leading to bacterial multidrug resistance. Antibiotics are effluxed out of the bacterial cell by a tripartite efflux pump, a complex machinery comprised of outer membrane, periplasmic adaptor, and inner membrane protein components. Understanding the mechanism of efflux pump assembly and its dynamics could facilitate discovery of novel approaches to...

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Identifiers

PMID: 29184094
DOI: 10.1038/s41598-017-16497-w
PMCID: PMC5705723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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