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Genetic factors that influence moenomycin production in streptomycetes

5 Mar 2010

Abstract excerpt

Moenomycin, a natural phosphoglycolipid product that has a long history of use in animal nutrition, is currently considered an attractive starting point for the development of novel antibiotics. We recently reconstituted the biosynthesis of this natural product in a heterologous host, Streptomyces lividans TK24, but production levels were too low to be useful. We have examined several other streptomycetes strains...

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PMID: 20204454
DOI: 10.1007/s10295-010-0701-1

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