Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetically engineered Streptomyces viridosporus ATCC 14672 strains for the discovery of novel moenomycins.

Scientific reports - 10 Mar 2026

Ostash Bohdan, Makitrynskyy Roman, Fedchyshyn Mariana, Luzhetskyy Andriy, Walker Suzanne, Fedorenko Victor

Abstract excerpt

Streptomyces viridosporus (formerly ghanaensis) ATCC14672 is the best-studied producer of moenomycins, a family of phosphoglycolipid natural products directly inhibiting peptidoglycan glycosyltransferases. The uniqueness of moenomycins, in terms of structure and mode of action, and their extreme potency against several Gram-positive pathogens (including vancomycin- and methicillin-resistant cocci), are their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Genetic Engineering

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Oligosaccharides

Share to Streptomyces

Source

Open in PubMed Open full text

Identifiers

PMID: 41807664
DOI: 10.1038/s41598-026-43988-6
PMCID: PMC13096315

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetically engineered Streptomyces viridosporus ATCC 14672 strains for the discovery of novel moenomycins.PMID 41807664Read ↗

Complete Characterization of the Seventeen Step Moenomycin Biosynthetic PathwaySemantic proximity Read ↗

Olikomycin A–A Novel Calcium‐Dependent Lipopeptide with Antibiotic Activity Against Multidrug‐Resistant BacteriaSemantic proximity Read ↗

[Genes for biosynthesis of butenolide-like signalling molecules in Streptomyces ghanaensis, their role in moenomycin production].Semantic proximity Read ↗

Genetic factors that influence moenomycin production in streptomycetesSemantic proximity Read ↗

Biosynthesis of desosamine: construction of a new macrolide carrying a genetically designed sugar moiety.Semantic proximity Read ↗

Streptomyces coelicolor Vesicles: Many Molecules To Be DeliveredSemantic proximity Read ↗

Induction of antimicrobial activities in heterologous streptomycetes using alleles of the Streptomyces coelicolor gene absA1.Semantic proximity Read ↗

Biosynthetic Pathway for Mannopeptimycins, Lipoglycopeptide Antibiotics Active against Drug-Resistant Gram-Positive PathogensSemantic proximity Read ↗

Characterization and heterologous expression of the neoabyssomicin/abyssomicin biosynthetic gene cluster from Streptomyces koyangensis SCSIO 5802Semantic proximity Read ↗

Engineered biosynthesis of glycosylated derivatives of narbomycin and evaluation of their antibacterial activities.Semantic proximity Read ↗

How To Make a Glycopeptide: A Synthetic Biology Approach To Expand Antibiotic Chemical DiversitySemantic proximity Read ↗

ABC transporter genes from Streptomyces ghanaensis moenomycin biosynthetic gene cluster: roles in antibiotic production and export.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.