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Advances in identification and selection of personalized neoantigen/T-cell pairs for autologous adoptive T cell therapies

1 Jan 2021

Abstract excerpt

Based on the success of tumor-infiltrating lymphocytes (TIL)-based therapies, personalized adoptive cell therapies (ACT) targeting neoantigens have the potential to become a disruptive technology and lead to highly effective treatments for cancer patients for whom no other options exist. ACT of TIL, peripheral blood or gene-engineered peripheral blood lymphocytes (PBLs) targeting neoantigens is a highly...

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PMID: 33520408
DOI: 10.1080/2162402x.2020.1869389

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