Article
Polymorphisms in GSTM1, CYP1A1, CYP2E1, and CYP2D6 are associated with susceptibility and chemotherapy response in non-small-cell lung cancer patients.
Lung - 1 Feb 2012
Li WeiYing, Yue WenTao, Zhang LiNa, Zhao XiaoTing, Ma Li, Yang XueHui, Zhang ChunYan, Wang Yue, Gu Meng
Abstract excerpt
BACKGROUND: Studies of polymorphisms in CYP1A1, CYP2E1, CYP2D6, and GSTM1 and their relationship to lung cancer susceptibility and chemotherapy response have been reported, but the results are not consistent. In this study we selected four polymorphisms in these genes, several of which have previously been researched, and investigated their association with lung cancer susceptibility and chemotherapy response....
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