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Article

Peroxisome proliferator-activated receptor-gamma coactivator-1alpha overexpression increases lipid oxidation in myocytes from extremely obese individuals.

Diabetes - 1 Jun 2010

Consitt Leslie A, Bell Jill A, Koves Timothy R, Muoio Deborah M, Hulver Matthew W, Haynie Kimberly R, Dohm G Lynis, Houmard Joseph A

Abstract excerpt

OBJECTIVE: To determine whether the obesity-related decrement in fatty acid oxidation (FAO) in primary human skeletal muscle cells (HSkMC) is linked with lower mitochondrial content and whether this deficit could be corrected via overexpression of peroxisome proliferator-activated receptor-gamma...

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Source

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Identifiers

PMID: 20200320
DOI: 10.2337/db09-1704
PMCID: PMC2874701

Genes

PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20200320-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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