Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ACSL5 genotype influence on fatty acid metabolism: a cellular, tissue, and whole-body study.

Metabolism: clinical and experimental - 1 Jun 2018

Rajkumar Abishankari, Liaghati Awa, Chan Jessica, Lamothe Gilles, Dent Robert, Doucet Éric, Rabasa-Lhoret Rémi, Prud'homme Denis, Harper Mary-Ellen, Tesson Frédérique

Abstract excerpt

BACKGROUND: Acyl-CoA Synthetase Long Chain 5 (ACSL5) gene's rs2419621 T/C polymorphism was associated with ACSL5 mRNA expression and response to lifestyle interventions. However, the mechanistic understanding of the increased response in T allele carriers is lacking. Study objectives were to investigate the effect of rs2419621 genotype and ACSL5 human protein isoforms on fatty acid oxidation and respiration....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Aged
Share to Cells, Cultured
Share to Coenzyme A Ligases
Share to Fatty Acids
Share to Lipid Metabolism
Share to Liver
Share to Mice
Share to Muscle Fibers, Skeletal

Source

Identifiers

PMID: 29605434
DOI: 10.1016/j.metabol.2018.03.019

Genes

ACSL5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ACSL5 genotype influence on fatty acid metabolism: a cellular, tissue, and whole-body study.PMID 29605434Read ↗

Genetic Variation of Human Long-Chain Fatty Acyl-CoA Synthetase and Nutritional Implication.Semantic proximity Read ↗

Acyl-CoA synthetase long-chain 5 genotype is associated with body composition changes in response to lifestyle interventions in postmenopausal women with overweight and obesity: a genetic association study on cohorts Montréal-Ottawa New Emerging Team, and Complications Associated with Obesity.Semantic proximity Read ↗

Functional characterization of a promoter polymorphism that drives ACSL5 gene expression in skeletal muscle and associates with diet-induced weight loss.Semantic proximity Read ↗

Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.Semantic proximity Read ↗

Gene-nutrient interactions with dietary fat modulate the association between genetic variation of the ACSL1 gene and metabolic syndrome.Semantic proximity Read ↗

The gene variant rs2419621 of ACYL-CoA synthetase long-chain 5 gene is associated with weight loss and metabolic changes in response to a robotic sleeve gastrectomy in morbid obese subjects.Semantic proximity Read ↗

Regulation of mitochondrial fatty acid β-oxidation in human: What can we learn from inborn fatty acid β-oxidation deficiencies?Semantic proximity Read ↗

The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.Semantic proximity Read ↗

Modification in mitochondrial function is associated with the FADS1 variant and its interaction with alpha-linolenic acid-enriched diet-An exploratory study.Semantic proximity Read ↗

Physiological variability in mitochondrial rRNA predisposes to metabolic syndromeSemantic proximity Read ↗

Peroxisome proliferator-activated receptor gamma 2 and acyl-CoA synthetase 5 polymorphisms influence diet response.Semantic proximity Read ↗

LMNA rs4641 and the muscle lamin A and C isoforms in twins--metabolic implications and transcriptional regulation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.