Article
Genetic variation in CYP11A1 and StAR in relation to endometrial cancer risk.
Gynecologic oncology - 1 May 2010
Terry Kathryn, McGrath Monica, Lee I-Min, Buring Julie, De Vivo Immaculata
Abstract excerpt
OBJECTIVE: Together, steroidogenic acute regulator (StAR) and the cholesterol side chain cleavage enzyme (P450scc), which is encoded by CYP11A1, mediate the initial and rate-limiting step in steroidogenesis. Given the role of estrogens in endometrial carcinogenesis, we hypothesized that genetic v...
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