Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants in ER cofactor genes and endometrial cancer risk.

PloS one - 1 Jan 2012

Li Yuqing, Low Hui-Qi, Foo Jia Nee, Darabi Hatef, Einarsdόttir Kristjana, Humphreys Keith, Spurdle Amanda, Easton Douglas F, Thompson Deborah J, Dunning Alison M, Pharoah Paul D P, Czene Kamila, Chia Kee Seng, Hall Per, Liu Jianjun

Abstract excerpt

Given that the transcriptional regulatory activity of estrogen receptor (ER) is modulated by its biochemical cofactors, genetic variation within the ER cofactor genes may alter cellular response to estrogen exposure and consequently modify the risk for endometrial cancer. We genotyped 685 tagging SNPs within 60 ER cofactor genes in 564 endometrial cancer cases and 1,510 controls from Sweden, and tested their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CREB-Binding Protein
Share to Endometrial Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endosomal Sorting Complexes Required for Transport

Share to Nedd4 Ubiquitin Protein Ligases

Share to Receptors, Estrogen

Share to Sweden

Share to Ubiquitin-Protein Ligases

Source

Open in PubMed Open full text

Identifiers

PMID: 22876322
DOI: 10.1371/journal.pone.0042445
PMCID: PMC3411617

Genes

NCOA2
CARM1
CREBBP
PRMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants in ER cofactor genes and endometrial cancer risk.PMID 22876322Read ↗

Exome-wide association study of endometrial cancer in a multiethnic population.Semantic proximity Read ↗

Breast cancer susceptibility polymorphisms and endometrial cancer risk: a Collaborative Endometrial Cancer Study.Semantic proximity Read ↗

Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.Semantic proximity Read ↗

Genetic polymorphisms and endometrial cancer risk.Semantic proximity Read ↗

Novel breast cancer risk alleles and endometrial cancer risk.Semantic proximity Read ↗

Common genetic variation in the sex hormone metabolic pathway and endometrial cancer risk: pathway-based evaluation of candidate genes.Semantic proximity Read ↗

Genome-wide association study of endometrial cancer in E2C2.Semantic proximity Read ↗

BRCA1-associated breast and ovarian cancer risks in Poland: no association with commonly studied polymorphisms.Semantic proximity Read ↗

Polymorphisms in genes hydroxysteroid-dehydrogenase-17b type 2 and type 4 and endometrial cancer risk.Semantic proximity Read ↗

GWAS meta-analysis of 16 852 women identifies new susceptibility locus for endometrial cancer.Semantic proximity Read ↗

Reproductive risk factors in breast cancer and genetic hormonal pathways: a gene-environment interaction in the MCC-Spain project.Semantic proximity Read ↗

Comprehensive genetic assessment of the ESR1 locus identifies a risk region for endometrial cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.