Article
Identification and characterization of Dlc1 isoforms in the mouse and study of the biological function of a single gene trapped isoform.
BMC biology - 3 Mar 2010
Sabbir Mohammad G, Wigle Nichola, Loewen Shauna, Gu Yuan, Buse Cordula, Hicks Geoffrey G, Mowat Michael R A
Abstract excerpt
BACKGROUND: The Dlc1 (deleted in liver cancer 1) tumour suppressor gene codes for a RhoGTPase activating protein that is found inactivated in many tumour types. Several transcriptional isoforms have been described but the functional significance and tissue distribution of each form is presently p...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
