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Article

DLC‐1:a Rho GTPase‐activating protein and tumour suppressor

1 Sept 2007

Abstract excerpt

Introduction Expression of DLC family proteins Features of DLC family protein domains Biological functions of DLC‐1 Genetic analysis of DLC‐1 function The DLC family proteins in cancer Conclusions and future directions Abstract The deleted in liver cancer 1 (DLC‐1) gene encodes a GTPase activating protein that acts as a negative regulator of the Rho family of small GTPases. Rho proteins transduce signals that...

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PMID: 17979893
DOI: 10.1111/j.1582-4934.2007.00098.x

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