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Article

The transforming growth factor-beta (TGF-β) mediates acquisition of a mesenchymal stem cell-like phenotype in human liver cells.

Journal of cellular physiology - 1 May 2011

Caja Laia, Bertran Esther, Campbell Jean, Fausto Nelson, Fabregat Isabel

Abstract excerpt

Transforming growth factor-beta (TGF-β) mediates several and sometime opposite effects in epithelial cells, inducing growth inhibition, and apoptosis but also promoting an epithelial to mesenchymal transition (EMT) process, which enhances cell migration and invasion. TGF-β plays relevant roles in different liver pathologies; however, very few is known about its specific signaling and cellular effects in human...

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Source

Identifiers

PMID: 20945437
DOI: 10.1002/jcp.22439

Genes

BMF
EGFR
XIAP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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