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Article

Transforming growth factor‐β in liver cancer stem cells and regeneration

21 Jul 2017

Abstract excerpt

Cancer stem cells have established mechanisms that contribute to tumor heterogeneity as well as resistance to therapy. Over 40% of hepatocellular carcinomas (HCCs) are considered to be clonal and arise from a stem‐like/cancer stem cell. Moreover, HCC is the second leading cause of cancer death worldwide, and an improved understanding of cancer stem cells and targeting these in this cancer are urgently needed....

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PMID: 29404474
DOI: 10.1002/hep4.1062

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