Article
Genetic predisposition to pancreatic cancer.
World journal of gastroenterology - 21 Aug 2014
Ghiorzo Paola
Abstract excerpt
Pancreatic adenocarcinoma (PC) is the most deadly of the common cancers. Owing to its rapid progression and almost certain fatal outcome, identifying individuals at risk and detecting early lesions are crucial to improve outcome. Genetic risk factors are believed to play a major role. Approximately 10% of PC is estimated to have familial inheritance. Several germline mutations have been found to be involved in...
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