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Article

Homozygous deletion of the STK11/LKB1 locus and the generation of novel fusion transcripts in cervical cancer cells.

Cancer genetics and cytogenetics - 1 Mar 2010

McCabe Michael T, Powell Doris R, Zhou Wei, Vertino Paula M

Abstract excerpt

The STK11/LKB1 gene encodes a ubiquitously expressed serine/threonine kinase that is mutated in multiple sporadic cancers including non-small cell lung carcinomas, pancreatic cancers, and melanomas. LKB1 plays a role in multiple cellular functions including cell growth, cell cycle progression, metabolism, cell polarity, and migration. To date, only a limited number of studies have assessed the status of LKB1 in...

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Source

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Identifiers

PMID: 20193846
DOI: 10.1016/j.cancergencyto.2009.11.017
PMCID: PMC2837085

Genes

SBNO2
STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Homozygous deletion of the STK11/LKB1 locus and the generation of novel fusion transcripts in cervical cancer cells.PMID 20193846Read ↗

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