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Article

Somatic LKB1 mutations promote cervical cancer progression.

PloS one - 1 Jan 2009

Wingo Shana N, Gallardo Teresa D, Akbay Esra A, Liang Mei-Chi, Contreras Cristina M, Boren Todd, Shimamura Takeshi, Miller David S, Sharpless Norman E, Bardeesy Nabeel, Kwiatkowski David J, Schorge John O, Wong Kwok-Kin, Castrillon Diego H

Abstract excerpt

Human Papilloma Virus (HPV) is the etiologic agent for cervical cancer. Yet, infection with HPV is not sufficient to cause cervical cancer, because most infected women develop transient epithelial dysplasias that spontaneously regress. Progression to invasive cancer has been attributed to diverse host factors such as immune or hormonal status, as no recurrent genetic alterations have been identified in cervical...

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Identifiers

PMID: 19340305
DOI: 10.1371/journal.pone.0005137
PMCID: PMC2660434

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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