Article
Searching for valid psychiatric phenotypes: discrete latent variable models.
International journal of methods in psychiatric research - 1 Jun 2010
Leoutsakos Jeannie-Marie S, Zandi Peter P, Bandeen-Roche Karen, Lyketsos Constantine G
Abstract excerpt
INTRODUCTION: A primary challenge in psychiatric genetics is the lack of a completely validated system of classification for mental disorders. Appropriate statistical methods are needed to empirically derive more homogenous disorder subtypes. METHODS: Using the framework of Robins and Guze's ('Es...
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