Article
Wernicke-Kleist-Leonhard phenotypes of endogenous psychoses: a review of their validity .
Dialogues in clinical neuroscience - 1 Mar 2020
Foucher Jack R, Gawlik Micha, Roth Julian N, de Crespin de Billy Clément, Jeanjean Ludovic C, Obrecht Alexandre, Mainberger Olivier, Clauss Julie M E, Elowe Julien, Weibel Sébastien, Schorr Benoit, Cetkovich Marcelo, Morra Carlos, Rebok Federico, Ban Thomas A, Bollmann Barbara, Roser Mathilde M, Hanke Markus S, Jabs Burkhard E, Franzek Ernst J, Berna Fabrice, Pfuhlmann Bruno
Abstract excerpt
While the ICD-DSM paradigm has been a major advance in clinical psychiatry, its usefulness for biological psychiatry is debated. By defining consensus-based disorders rather than empirically driven phenotypes, consensus classifications were not an implementation of the biomedical paradigm. In the field of endogenous psychoses, the Wernicke-Kleist-Leonhard (WKL) pathway has optimized the descriptions of 35 major...
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