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Article

A general framework for formal tests of interaction after exhaustive search methods with applications to MDR and MDR-PDT.

PloS one - 23 Feb 2010

Edwards Todd L, Turner Stephen D, Torstenson Eric S, Dudek Scott M, Martin Eden R, Ritchie Marylyn D

Abstract excerpt

The initial presentation of multifactor dimensionality reduction (MDR) featured cross-validation to mitigate over-fitting, computationally efficient searches of the epistatic model space, and variable construction with constructive induction to alleviate the curse of dimensionality. However, the...

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Identifiers

PMID: 20186329
DOI: 10.1371/journal.pone.0009363
PMCID: PMC2826406

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20186329-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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