Article
Rapid multiplex real-time PCR by molecular beacons for different BRAF allele detection in papillary thyroid carcinoma.
Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Mar 2010
Orru Germano, Coghe Ferdinando, Faa Gavino, Pillai Sara, Manieli Cristina, Montaldo Caterina, Pilia Francesca, Pichiri Giuseppina, Piras Vincenzo, Coni Pierpaolo
Abstract excerpt
BRAF is an oncogene that is commonly mutated in both melanomas and papillary thyroid carcinomas (PTCs). Usually, mutations in the codons 600 or 601 lead to constitutive activity in the Ras-mitogen-activated protein kinase pathway and, recently, the BRAF deletion was described as a relevant risk f...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
