Article
BRAF mutations in melanocytic lesions and papillary thyroid carcinoma samples identified using melting curve analysis of polymerase chain reaction products.
Archives of pathology & laboratory medicine - 1 Sept 2007
Hay Robert, MacRae Erin, Barber Duane, Khalil Moosa, Demetrick Douglas J
Abstract excerpt
CONTEXT: Mutations of the proto-oncogene B-raf (BRAF) have been detected in melanocytic lesions and papillary carcinomas of the thyroid, and identification of these mutations could be useful in resolving some diagnostic problems. OBJECTIVE: To develop a method to evaluate mutations of BRAF that c...
Topics
- Base Sequence
- Biopsy, Fine-Needle
- Carcinoma, Papillary
- DNA, Neoplasm
- Humans
- Melanoma
- Molecular Sequence Data
- Mutation
- Nevus, Pigmented
- Polymerase Chain Reaction
- Proto-Oncogene Mas
- Proto-Oncogene Proteins B-raf
- Skin Neoplasms
- Thyroid Neoplasms
