Article
BRAF mutations in melanocytic lesions and papillary thyroid carcinoma samples identified using melting curve analysis of polymerase chain reaction products.
Archives of pathology & laboratory medicine - 1 Sept 2007
Hay Robert, MacRae Erin, Barber Duane, Khalil Moosa, Demetrick Douglas J
Abstract excerpt
CONTEXT: Mutations of the proto-oncogene B-raf (BRAF) have been detected in melanocytic lesions and papillary carcinomas of the thyroid, and identification of these mutations could be useful in resolving some diagnostic problems. OBJECTIVE: To develop a method to evaluate mutations of BRAF that could provide results much more rapidly than conventional polymerase chain reaction and DNA sequencing assays. DESIGN:...
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