Article
Significance of allelic percentage of BRAF c.1799T > A (V600E) mutation in papillary thyroid carcinoma.
Annals of surgical oncology - 1 Dec 2014
Cheng Shih-Ping, Hsu Yi-Chiung, Liu Chien-Liang, Liu Tsang-Pai, Chien Ming-Nan, Wang Tao-Yeuan, Lee Jie-Jen
Abstract excerpt
BACKGROUND: Somatic BRAF mutation is frequently observed in papillary thyroid carcinoma (PTC). Recent evidence suggests that PTCs are heterogeneous tumors containing a subclonal or oligoclonal occurrence of BRAF mutation. Conflicting results have been reported concerning the prognostic significance of the mutant allele frequency. Our present aim was to investigate the association between the percentage of BRAF...
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