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Article

Variants in ASK1 are associated with skeletal muscle ASK1 expression, in vivo insulin resistance, and type 2 diabetes in Pima Indians.

Diabetes - 1 May 2010

Bian Li, Hanson Robert L, Ossowski Victoria, Wiedrich Kim, Mason Clinton C, Traurig Michael, Muller Yunhua L, Kobes Sayuko, Knowler William C, Baier Leslie J, Bogardus Clifton

Abstract excerpt

OBJECTIVE: Prior genome-wide association and exon array expression studies both provided suggestive evidence that apoptosis signal regulating kinase 1 (ASK1) may influence in vivo insulin action in Pima Indians. Genetic variants in or near ASK1 were analyzed to assess the role of this gene in ins...

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Share to Diabetes Mellitus, Type 2
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Indians, North American

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Share to Muscle, Skeletal

Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 20185809
DOI: 10.2337/db09-1700
PMCID: PMC2857909

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20185809-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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