Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The molecular basis of beta-thalassemia intermedia in southern China: genotypic heterogeneity and phenotypic diversity.

BMC medical genetics - 25 Feb 2010

Chen Wanqun, Zhang Xinhua, Shang Xuan, Cai Ren, Li Liyan, Zhou Tianhong, Sun Manna, Xiong Fu, Xu Xiangmin

Abstract excerpt

BACKGROUND: The clinical syndrome of thalassemia intermedia (TI) results from the beta-globin genotypes in combination with factors to produce fetal haemoglobin (HbF) and/or co-inheritance of alpha-thalassemia. However, very little is currently known of the molecular basis of Chinese TI patients. METHODS: We systematically analyzed and characterized beta-globin genotypes, alpha-thalassemia determinants, and known...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Thalassemia
Share to beta-Globins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to beta-Thalassemia

Share to DNA Primers

Share to Fetal Hemoglobin

Share to Haplotypes

Share to Hemoglobin E

Source

Open in PubMed Open full text

Identifiers

PMID: 20181291
DOI: 10.1186/1471-2350-11-31
PMCID: PMC2845123

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The molecular basis of beta-thalassemia intermedia in southern China: genotypic heterogeneity and phenotypic diversity.PMID 20181291Read ↗

[A rare thalassemia intermedia case caused by co-existence of Hb H disease (--(SEA)/-alpha(4.2)) and beta-thalassemia major (beta (CD17A)>T/beta (IVS2-654C)>T): implications for prenatal diagnosis].Semantic proximity Read ↗

Multicenter study of the molecular basis of thalassemia intermedia in different ethnic populations.Semantic proximity Read ↗

[Molecular analysis of beta-thalassemia intermedia in Guangdong Province].Semantic proximity Read ↗

Molecular basis of thalassemia intermedia in Iran.Semantic proximity Read ↗

Molecular mechanisms underlying thalassemia intermedia in Iran.Semantic proximity Read ↗

Association between Different Polymorphic Markers and β-Thalassemia Intermedia in Central Iran.Semantic proximity Read ↗

Hematological and genetic basis of clinical heterogeneity of HemoglobinE/β-thalassemia in BangladeshSemantic proximity Read ↗

Molecular analysis of alpha- and beta-thalassemia in Meizhou region and comparison of gene mutation spectrum with different regions of southern China.Semantic proximity Read ↗

Genetic research and clinical analysis of β-globin gene cluster deletions in the Chinese population of Fujian province: A 14-year single-center experience.Semantic proximity Read ↗

Molecular understanding of Indian untransfused thalassemia intermedia.Semantic proximity Read ↗

Molecular spectrum of α- and β-globin gene mutations detected in the population of Guangxi Zhuang Autonomous Region, People's Republic of China.Semantic proximity Read ↗

Molecular epidemiological and hematological profile of thalassemia in the Dongguan Region of Guangdong Province, Southern China.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.