Molecular epidemiological and hematological profile of thalassemia in the Dongguan Region of Guangdong Province, Southern China.

doi:10.1002/jcla.23596

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Article

Molecular epidemiological and hematological profile of thalassemia in the Dongguan Region of Guangdong Province, Southern China.

Journal of clinical laboratory analysis - 1 Feb 2021

Peng Qi, Zhang Zhenhong, Li Siping, Cheng Chuyun, Li Wenrui, Rao Chunbao, Zhong Baimao, Lu Xiaomei

Abstract excerpt

BACKGROUND: Thalassemia is a common inherited hematological disease in tropical and subtropical regions. This study aimed to investigate the mutation spectrum of thalassemia in the Dongguan region of southern China and comprehensively analyze hematologic features of thalassemia carriers with various types of globin mutations. METHODS: A hematological screening including hematological indices such as mean...

Topics

Adolescent
Adult
Aged
Child
Child, Preschool
China
Erythrocyte Indices
Female
Gene Frequency
Genotype
Glycated Hemoglobin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Middle Aged

Mutation

Prevalence

Young Adult

alpha-Globins

Source

Open in PubMed Open full text

Identifiers

PMID: 32986258
DOI: 10.1002/jcla.23596
PMCID: PMC7891532

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