Article
Molecular mechanisms underlying thalassemia intermedia in Iran.
Genetic testing - 1 Dec 2008
Neishabury Maryam, Azarkeivan Azita, Oberkanins Christian, Esteghamat Fatemehsadat, Amirizadeh Naser, Najmabadi Hossein
Abstract excerpt
To improve the differentiation of thalassemia intermedia from other hemoglobinopathies in Iran, four known genetic mechanisms-XmnI (G)gamma polymorphism, inheritance of mild and silent beta-thalassemia alleles, delta beta deletion, and coinheritance of alpha- and beta-thalassemia-were investigate...
Topics
- Adolescent
- Adult
- Alleles
- Base Sequence
- Child
- DNA Mutational Analysis
- DNA Primers
- Female
- Genotype
- Hemoglobin Subunits
- Humans
- Iran
- Male
- Middle Aged
- Mutation
- Phenotype
- Thalassemia
- Young Adult