Article
Molecular basis of thalassemia intermedia in Iran.
Hemoglobin - 1 Jan 2008
Akbari Mohammad T, Izadi Pantea, Izadyar Mina, Kyriacou Kyriacou, Kleanthous Marina
Abstract excerpt
Thalassemia intermedia shows considerable heterogenity in phenotype and molecular basis. The aim of this study was to evaluate the prevalence and effect of different beta-globin mutations, alpha-globin defects and (G)gamma XmnI polymorphisms in Iranian patients. Forty-five Iranian patients with clinical criteria of thalassemia intermedia were studied. The molecular background of the diseases was investigated. The...
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