Article
Molecular understanding of Indian untransfused thalassemia intermedia.
International journal of laboratory hematology - 1 Dec 2015
Nadkarni A, Dabke P, Colah R, Ghosh K
Abstract excerpt
BACKGROUND: The term thalassemia intermedia describe a form of thalassemia of intermediate severity, between the major transfusion-dependent forms of the disease and the symptomless carrier states. The phenotypic diversity of β-thalassemia results from its underlying genetic diversity. The wide clinical variability of these conditions leads to major difficulties in their management. The molecular basis of...
Topics
- Adolescent
- Adult
- Blood Transfusion
- Child
- Child, Preschool
- Female
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Haplotypes
- Humans
- India
- Male
- Mutation
- Phenotype
- Polymorphism, Genetic
- Severity of Illness Index
- Thalassemia