Article
[Molecular analysis of beta-thalassemia intermedia in Guangdong Province].
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics - 1 Aug 2007
Zhang Li, Ou Xiao-Bing, Yu Yi-Ping
Abstract excerpt
OBJECTIVE: To determine the molecular defects of beta-thalassemia intermedia in Guangdong Province and to provide basis for gene diagnosis and gene therapy of this disorder. METHODS: DNA analysis of the alpha, beta and gamma globin genes was performed in 18 children with beta-thalassemia intermedia from Guangdong Province using polymerase chain reaction (PCR), microarray technique, Southern blot and direct...
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