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Article

Tumor necrosis factor-alpha promoter variants and iron phenotypes in 785 hemochromatosis and iron overload screening (HEIRS) study participants.

Blood cells, molecules & diseases - 15 Apr 2010

Acton Ronald T, Barton James C, Leiendecker-Foster Catherine, Zaun Christopher, McLaren Christine E, Eckfeldt John H

Abstract excerpt

We sought to determine if TNF promoter variants could explain iron phenotype heterogeneity in adults with previous HFE genotyping. HEIRS Study participants genotyped for C282Y and H63D were designated as high transferrin saturation (TS) and/or serum ferritin (SF) (high TS/SF), low TS/SF, or controls. We grouped 191 C282Y homozygotes as high TS/SF, low TS/SF, or controls, and 594 other participants by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20178892
DOI: 10.1016/j.bcmd.2010.01.007
PMCID: PMC3836206

Genes

TNF
HFE

Variants

Provenance

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